From Harrison County, trucks can easily distribute products to 75% of the U.S. market within 24 hours.
- U.S. 49 – major north-south highway, connects Harrison County to Hattiesburg, Jackson and beyond. It runs past the Gulfport-Biloxi International Airport and directly into the Port of Gulfport.
- Interstate 10 – major east-west interstate, runs directly through Harrison County, intersecting U.S. 49 and linking Jacksonville, Fla. to Los Angeles, Calif.
- Interstate 59 – runs north-south and crosses through Pearl River County extending from Lookout Mountain, Ga. to Slidell, La.
- Interstate 65 – located just outside Mississippi, in Alabama, runs north-south, reaching to Indiana.